By Maya
Feeling worn out all the time? You’re not alone. Fatigue is one of the most common complaints people bring to their doctors—draining productivity, mood, motivation, and overall quality of life. While addressing sleep, nutrition, stress, and medical causes is essential, natural supplements can be a gentle, effective way to support your energy systems and help you feel like yourself again.
Below are two evidence-based options that many people with fatigue find helpful.
Rhodiola rosea
Rhodiola is an adaptogenic herb traditionally used to combat physical and mental exhaustion. It appears to help the body respond better to stress while supporting mitochondrial energy production, which can translate into more stable day-to-day energy and improved focus.
- Mechanism of action: Modulates the stress response (HPA axis) and supports cellular energy production.
- Dosage or usage tip: Start with 200–400 mg/day of a standardized extract (typically ~3% rosavins, 1% salidroside), taken in the morning or early afternoon to avoid interfering with sleep.
- Buy link: [Buy Rhodiola rosea here]
Coenzyme Q10 (CoQ10 / Ubiquinol)
CoQ10 is a key cofactor in mitochondrial ATP production—the biochemical process that turns food into usable energy. Low CoQ10 levels are associated with increased fatigue, and supplementation has been shown to improve energy in certain populations (e.g., statin users, people with chronic fatigue-like symptoms).
- Mechanism of action: Enhances mitochondrial ATP synthesis and acts as an antioxidant to reduce oxidative stress.
- Dosage or usage tip: 100–200 mg/day, preferably in the ubiquinol form for better absorption, taken with a meal containing fat.
- Buy link: [Buy CoQ10 here]
Summary
If fatigue is disrupting your life, Rhodiola rosea (for stress resilience and mental stamina) and CoQ10 (for mitochondrial energy production) are two well-researched supplements worth considering. Pair them with foundational habits—consistent sleep, balanced nutrition, movement, and stress management—for the best results. Always consult a qualified healthcare professional before starting new supplements, especially if you take medications, are pregnant or breastfeeding, or suspect an underlying medical condition such as anemia, thyroid dysfunction, sleep apnea, or depression.
Medical disclaimer: This article is for informational purposes only and does not constitute medical advice.