Best Supplements for Yellowing of Skin

By Elise

Yellowing of the skin, also known as jaundice, occurs when there is a buildup of bilirubin in the body. This can happen due to liver issues, bile duct blockage, certain blood disorders, or other medical conditions. While the symptom can range from mild to severe, it is always important to seek medical evaluation promptly, as jaundice can be a sign of serious underlying health problems.

Alongside professional treatment, certain natural supplements may help support liver function, promote detoxification, and protect cells from oxidative damage. Here are two evidence-based options that may provide supportive benefits for overall liver and skin health.

Milk Thistle

Milk thistle is one of the most well-researched herbal supplements for liver support. It contains silymarin, a powerful antioxidant compound that helps protect liver cells from damage and supports their regeneration.

  • Mechanism of action: Protects liver cells from toxins, reduces oxidative stress, and supports the regeneration of healthy liver tissue.
  • Dosage or usage tip: Commonly taken at 200–400 mg of standardized silymarin extract daily, divided into two doses.
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N-Acetylcysteine (NAC)

N-Acetylcysteine is an amino acid that acts as a precursor to glutathione, the body’s most important antioxidant for detoxification. It supports the liver in processing toxins and helps maintain healthy bile flow, which can be beneficial when bilirubin levels are elevated.

  • Mechanism of action: Increases glutathione production, supports detoxification pathways, and protects liver cells from oxidative damage.
  • Dosage or usage tip: Typically taken at 600–1,200 mg daily, divided into two doses.
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Summary:

Yellowing of the skin should never be ignored, as it can indicate underlying liver or bile duct issues. Once your healthcare provider identifies the cause, supplements like Milk Thistle and N-Acetylcysteine may help support liver health, protect cells from oxidative stress, and promote healthy detoxification.

Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting any new supplement, especially if you notice sudden or worsening yellowing of the skin.